Two studies, one by Walther1 and the other by Mérle,2 stand out prominently among the contributions to the subject of ependymitis. In the first, the author draws attention to the so-called acute purulent ependymitis. He regards it as rather frequent in association with a coexistent inflammatory process elsewhere in the brain or meninges, and rare as an independent or definitely local inflammatory lesion in the ventricular lining of the brain. Without establishing any definite relationship between it and the more common, so-called chronic, form of ependymitis, he opens the discussion of the second form by subgrouping it into two types: (1) chronic diffuse sclerosing ependymitis, and (2) chronic granular ependymitis. He emphasizes the lack of sharp lines of division between these two types, since there are many transitional forms. In diffuse ependymal sclerosis, the ependyma is thickened, sclerosed over extensive areas and presents a smooth, though somewhat
GLOBUS JH, STRAUSS I. SUBACUTE DIFFUSE EPENDYMITIS: REPORT OF A CASE SIMULATING TUMOR OF THE BRAIN. Arch NeurPsych. 1928;19(4):623–637. doi:10.1001/archneurpsyc.1928.02210100052004
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