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August 1928

CENTRAL NEURITISITS ETIOLOGY AND SYMPTOMATOLOGY

Arch NeurPsych. 1928;20(2):366-391. doi:10.1001/archneurpsyc.1928.02210140134011
Abstract

Historical review.

The clinical classification of cases studied.

The microscopic changes of central neuritis.

Report of cases.

The symptom-complex of central neuritis.

Neurologic symptoms.

Systemic symptoms.

Mental symptoms.

The etiology of central neuritis.

Possible etiologic factors.

Axonal injury.

Toxins, endogenous and exogenous.

Infection.

Type of terminal illness.

Starvation.

Theoretical considerations.

A new name for central neuritis.

Summary.

Conclusions.

The pathologic process known as "central neuritis" involves particularly the ganglion cells and resembles the change found in the cell body of a peripheral neuron after injury to its axon. As the involvement frequently seems severe enough to interfere with function, one would expect that its presence could be detected during life. Although central neuritis is found in many different diseases, there must be a common etiologic factor. In this study, I investigated central neuritis from two points of view: (1) diagnosis during life, and (2) etiology.

HISTORICAL REVIEW  Central neuritis was

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