I shall present a study of the microscopic changes in four cases of neurosyphilis showing hyaline degeneration of the blood vessels of the brain. Vascular changes of this type in neurosyphilis are comparatively rare, only a few cases having hitherto been recorded in the literature. This fact and also the rare and unusually sharp restriction of the hyaline degeneration to certain circumscribed areas of the cortex in my first case seemed to justify this report.
REPORT OF CASE
Case 1.—History.
—C. C., a shoemaker, aged 52, was admitted to the hospital on Jan. 28, 1924. The parents were both half-Indians. Two half-aunts and one half-uncle were insane and in state hospitals (the exact nature of the condition could not be ascertained). Development apparently was normal, although the patient had attained only a low average intellectual level. There were no neurotic or psychopathic trends. The previous medical history was unimportant. The