It is well established that paresis is favorably influenced by treatment with malaria. This influence from the clinical standpoint is so marked that in many cases the patient reaches a condition of complete remission or social recovery. Clinical and serologic data of the results of this special treatment may be found in the series of articles of Kirby and Bunker,1 from cases in the Psychiatric Institute, and in my own papers in collaboration with Fong2 from those of St. Elizabeth's Hospital, Washington, D. C. In this paper it is my purpose to consider exclusively the histologic changes following treatment with malaria.
While numerous papers have been written on the clinical aspects of this new type of treatment, comparatively few authors have paid special attention to the histologic changes. In this country, only two papers have been published, one by Lewis, Hubbard and Dyar3 dealing with four cases