Francois-Franck1 justly stated that the vascular innervation of the central nervous system may conveniently be studied on the blood vessels of the pia, for the latter "practically belong to the brain substance itself." It must also be conceded that the vasomotor nerves of the pia are derived from the cervical sympathetic nerve supply of the internal carotid and the vertebral arteries; the vertebral system innervates the blood vessels of the pons, medulla and cerebellum; the carotid system supplies the rest of the cerebral vessels. The pia receives additional—parasympathetic—nerves from the third, seventh, ninth and tenth, and also some fibers from the sixth, eleventh and twelfth cranial nerves. Some nerves have apparently nothing to do with the vascular innervation, for they end freely in the connective tissue. Some such fibers are most likely sensory.
METHODS OF STUDY
Ordinary dissecting methods of studying the vascular nerves can be applied only to
HASSIN GB. THE NERVE SUPPLY OF THE CEREBRAL BLOOD VESSELS: A HISTOLOGIC STUDY. Arch NeurPsych. 1929;22(2):375–391. doi:10.1001/archneurpsyc.1929.02220020191011
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