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November 1929

THE NERVOUS REGULATION OF SUGAR METABOLISM: II. EXPERIMENTAL STUDIES

Author Affiliations

CHICAGO

From the Division of Neurology of the Department of Medicine and the Douglas Smith Fund of the University of Chicago.

Arch NeurPsych. 1929;22(5):919-925. doi:10.1001/archneurpsyc.1929.02220050057004
Abstract

In a previous communication Hiller and Tannenbaum1 repeated and amplified the experiments of Claude Bernard, who considered, as a result of his piqûre of the medulla, that a medullary sugar center existed. For the first time they most carefully controlled each factor in the piqûre and concluded finally that an irritation of the dorsal vagus nucleus as a hypothetic center for sugar metabolism did not lead to an increase in blood sugar. Thus the age old conception of a medullary sugar center from physiologic evidence must be abandoned.

In 1920, Brugsch, Dresel and Lewy2 attacked the problem from another angle in order to obtain verification of their experiments confirming the presence of a sugar center in the medulla. They sought to show anatomically the intimate relationship between the vagus nerve, the sympathetic cervical trunk, the dorsal vagus nucleus and the visceral centers in the 'tween-brain. The purpose of

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