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March 1930

COCCIDIOIDAL GRANULOMAREPORT OF TWO CASES SIMULATING TUMOR OF THE SPINAL CORD

Author Affiliations

LOS ANGELES

Arch NeurPsych. 1930;23(3):502-511. doi:10.1001/archneurpsyc.1930.02220090093005
Abstract

Cases of coccidioidal granuloma are of increasing interest to those of us living in California. The disease was first described by Posadas1 in Buenos Aires in 1900, the same case having been observed and reported independently by Wernicke2 in 1892. Rixford,3 in 1894, recognized the first case in California. This case with another observed by Thorne4 was described later in greater detail by Rixford and Gilchrist,5 who believed that the infecting organism was a protozoan belonging to the group of Coccidia, and suggested the name of Coccidioides immitis for the organism. Ophüls and Moffit,6 in 1900, observed another case and found that the parasite grew readily on artificial mediums and developed a mold. It apparently belonged to the group of Oidia. Ophüls7 then gave the name of Oidium coccidioides to the parasitic organism and coccidioidal granuloma to the lesion produced by it.

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