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Young dogs, operated on by Rademaker in the laboratory of Magnus, were kept alive long enough to permit secondary degeneration to occur according to the principle of von Gudden and von Monakow. The operations were performed in stages, and in each dog the cerebellum and both cerebral hemispheres were removed; in addition, in one dog the corpus striatum was removed on one side, while in the other dog the corpus striatum was completely removed on one side and partially removed on the other side. These are the first dogs described in the literature that have survived for any length of time such extensive extirpations; the dog of Pavlov, in which the cerebellum was intact, and the dogs of Goltz, Munk and Rothmann, in which the cerebellum or parts of the cerebrum remained, are compared with them. In these two dogs, "Robbie" and "Duimelot," the clinical symptoms were different because of