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The subject matter of this book is divided into four nearly equal parts. Part 1 concerns the methods of obtaining fluid from different loci and a consideration of the various tests. It is noteworthy that in this chapter the various colloidal reactions find no place, brief discussion of them being relegated to the chapter on neurosyphilis.
Parts 2 and 3 form the significant part of the monograph and deal with the physiology of the cerebrospinal fluid, from the point of view of both animal experimentation and observations on man. In these chapters the work of earlier workers is discussed, which includes many references to the American literature, and also the presentation of the author's observations. He accepts the choroid plexus as the chief source of origin of the fluid, and admits the perivascular origin as probable though not proved. Personal experiments prove the lack of deep penetration into the brain