[Skip to Content]
[Skip to Content Landing]
December 1930


Author Affiliations


From the Neurological Institute of New York.

Arch NeurPsych. 1930;24(6):1187-1198. doi:10.1001/archneurpsyc.1930.02220180084006

Scleroderma as a disease entity is scoffed at by most authorities. The general conclusion is that it belongs to the class of trophoneurotic and angiotrophoneurotic disturbances with the outstanding characteristic of a nutritional disturbance of the skin leading to atrophy, induration and other anomalies. Like most other angioneuroses and trophoneuroses, the condition is rare. Oppenheim,1 Steiner2 and others called attention to the relationship of the scleroderma syndrome to dermatomyositis and to this condition as a possible sequel of dermatomyositis. Hoover3 described several cases of dermatomyositis, which, from his description, also had the characteristic skin changes of scleroderma. In the course of several years, a number of cases of dermatomyositis, dermatoneuromyositis and scleroderma have been seen at the Lakeside Hospital in Cleveland, St. Joseph's Mercy Hospital in Ann Arbor and the Neurological Institute of New York; attention was attracted by out-standing characteristics that these three conditions have in