Although there are numerous reports on the hereditary factors in manic-depressive psychosis, on the age of the patient at onset, the length of the attacks and the length of the intervals, the reports dealing with possible correlations between the hereditary factors and the other factors mentioned are extremely rare. In a disorder, the hereditary factors of which are so prominent and so varied, it is only natural to ask whether a certain type of heredity is related to a certain clinical course of disease. In other words, can one predicate the occurrence of a severe clinical course on the presence of severe familial neuropathic factors, or is the course of the disease unrelated to these? A search of the literature revealed but few replies to these questions. In text-books, such as those by Ziehen, Pilcz, Stransky, Strohmayer, Kraepelin, Bleuler and Lange, no possible correlation between these factors was mentioned. A
PASKIND HA. MANIC-DEPRESSIVE PSYCHOSIS: THE RELATION OF HEREDITARY FACTORS TO THE CLINICAL COURSE. Arch NeurPsych. 1931;25(1):145–147. doi:10.1001/archneurpsyc.1931.02230010157009
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