In this article I shall deal with some acute cases of cerebral disease in which multiple lesions of vascular origin, electively localized in the cortical gray matter, form the most interesting part of, or even the entire, pathologic process. The etiology varies; in two cases toxemia of pregnancy was the probable cause; in one case encephalitis and in one case severe shock with fall of the blood pressure. One patient died in the acute stage; the others survived from four to eight weeks.
There is still considerable confusion in the literature about the rôle played by primary blood vessel disease in cerebral lesions, evidenced, for instance, by the tenacity with which the term encephalitis hemorrhagica is being used for conditions in which no inflammation is present (case 1). On the other hand, it is difficult to recognize during life which part of the symptoms in a case of brain disease
DE VRIES E. ACUTE DISEASES OF THE BRAIN DUE TO FUNCTIONAL DISTURBANCE OF THE CIRCULATION: LAMINATED CORTICAL DISEASE. Arch NeurPsych. 1931;25(2):227–254. doi:10.1001/archneurpsyc.1931.02230020013001
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