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March 1931

DIFFUSE PROGRESSIVE DEGENERATION OF THE GRAY MATTER OF THE CEREBRUM

Author Affiliations

Traveling Fellow of the Frances Clark Fund for Neurosurgery PHILADELPHIA

From the Anatomical Laboratory of Prof. A. Jakob, Staatskrankenanstalt, Hamburg-Friedricksberg and the Neurosurgical Laboratory of Prof. C. H. Frazier, University Hospital, Philadelphia.

Arch NeurPsych. 1931;25(3):469-505. doi:10.1001/archneurpsyc.1931.02230030027002
Abstract

Knowledge of the pathology of numerous nervous disorders in infants is still in an insecure state. Save for a few diseases, little is known of the factors behind the production of organic nervous disease in infants. Every case studied from a pathologic standpoint is of interest because of the light it may throw on the neuropathology of these disorders. Consequently, the present case is reported as an addition to the knowledge of the pathology of the infantile brain.

REPORT OF CASE1 

Clinical History.  —A girl, aged 3 months, was admitted to the Hamburg Säuglingsheim in Barmbeck. The parents were apparently normal. The mother, aged 30, was said to be nervous, and the father, aged 27, was healthy. The child was the first-born, and the birth was normal in every respect. During the first few weeks, development was normal. The patient took feedings regularly, first by breast and later artificially.

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