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This monograph brings the author's excellent book, "The Internal Secretions of the Sex Glands," 1924, up to date. The success of ovarian transplantation differs in different species of animals. With proper technical precautions, almost 100 per cent of takes may be attained with homotrasplantations in the guinea-pig, even when the ovary is transplanted into a male. On the other hand, the proportion of success in rabbits is very small. In guinea-pigs, about 70 per cent of the successful takes are apparently still functioning after nine months. The animals receiving the transplants cannot be said to return to complete sexual normality. Heterotransplantations have never been anatomically proved successful, although it is possible that in the process of absorption they may yield hormones. It is not certain whether primary follicles appear in the transplanted ovary. Ovary preserved on ice may take root and grow, but the proportion of failures steadily increases as