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This monograph takes up in an orderly manner the changes in the blood vessels and in the tissues of the brain resulting from the wear and tear of age, known under the collective term of arteriosclerosis. There is nothing startlingly new in the book, but it is rather a collection of typical cases of various sorts to illustrate the varied types of change that may occur in the large and small blood vessels. The book is divided into two main divisions: In the first portion of the monograph, the changes in the blood vessels themselves are considered under the following heads: atherosclerosis, arteriosclerosis, capillary fibrosis, endarteritis of the small vessels and calcification. The second part of the book deals with the changes that result in the brain from the disease of the vessels. This is divided into: anemic necrosis, red infarct, incomplete necrosis, small "Verödung," encephalitis subcorticalis chronica, état vermoulu,