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May 1932

THE ACTION OF CERTAIN DRUGS: ON THE CEREBROSPINAL FLUID AND ON THE INTERNAL JUGULAR VENOUS AND SYSTEMIC ARTERIAL PRESSURES OF MAN

Author Affiliations

BOSTON

From the Research Laboratory of the Boston State Hospital and the Department of Neurology, Tufts Medical School.

Arch NeurPsych. 1932;27(5):1226-1244. doi:10.1001/archneurpsyc.1932.02230170242008
Abstract

In a previous paper1 we described the technic of measuring the pressure within the internal jugular vein and demonstrated that when combined with the cerebrospinal fluid and intracarotid pressures it constituted a clinical approach to the study of certain phases of the dynamics of the cerebral circulation.

Although the internal jugular vein lies outside the cranial cavity and does not measure accurately the true cerebral venous pressure, it lies so close to the cerebral sinuses that for all practical purposes we believe that the reading obtained at the site punctured (a matter of a few millimeters from the sinuses) must reflect closely the dynamics of the cerebral veins. Our previous experiments, recorded in the article cited, confirm this belief almost to the point of certainty, since those procedures, which in animals alter the pressure within the cerebral sinuses, alter the pressure within the human internal jugular vein in identical

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