The demonstration of abnormalities of the pulse rate in progressive muscular dystrophy is an added diagnostic point in doubtful cases. What follows emphasizes this. Goodhart and Globus1 showed in 1918 and Globus2 in 1923 that the heart muscle is diseased in muscular dystrophy. In 1929, Boas3 published pulse curves during sleep, cardiotachometrically obtained, and demonstrated the great drop that normally occurs. In 1928, Boas4 described the cardiotachometer, an instrument that can count automatically all of the pulse beats for indefinite periods of time. In 1931, Boas5 published reports of seven cases of muscular dystrophy in which the normal drop during sleep was absent. It is therefore not unexpected to find such curves as are here given. Figure 1 is from one of Boas' cases; figures 2 and 3, from a case observed by me on the neurologic wards at Bellevue Hospital (service of Dr. Foster
Kraus WM. THE PULSE CURVE IN A CASE OF PROGRESSIVE MUSCULAR DYSTROPHY. Arch NeurPsych. 1932;27(6):1444–1446. doi:10.1001/archneurpsyc.1932.02230180173012
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