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July 1932

BASAL METABOLIC RATE IN EPILEPSY: REPORT OF THREE HUNDRED AND FIFTY CASES

Author Affiliations

SONYEA, N. Y.

From the Department of Pathology of Craig Colony.

Arch NeurPsych. 1932;28(1):120-124. doi:10.1001/archneurpsyc.1932.02240010128008
Abstract

Endocrinopathies are being mentioned more and more in the literature as possible etiologic factors in convulsive disorders. One of the simplest tests for an endocrine dysfunction is measurement of the amount of oxygen that a person consumes or determination of the basal metabolic rate. The study of basal metabolism is considered by many to be only a test of thyroid activity. However, evidence is fast accumulating to show that the basal metabolic rate is also influenced by disturbances of the other glands of internal secretion, such as the gonads, the suprarenals and the pituitary.

Comparatively few reports have been made regarding the basal metabolism in epilepsy, and they are at such wide variance that one is inclined to discount the suggestion that there is any constant change in this disease.

In 1922, Boothby and Sandiford,1 working at the Mayo Clinic with 22 epileptic patients, found that the rate in

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