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August 1932

CHOLESTEROL CONTENT OF BLOOD IN EPILEPSY AND IN FEEBLEMINDEDNESS

Author Affiliations

SAN FRANCISCO; DALLAS, TEXAS

From the Stanford University School of Medicine, San Francisco, and the Presbyterian Hospital, Chicago.

Arch NeurPsych. 1932;28(2):357-369. doi:10.1001/archneurpsyc.1932.02240020109007
Abstract

Fat metabolism in epilepsy merits intensive investigation because of:

  1. The unappreciated frequency of paroxysmal disorders. These troubles include not only the grand mal of deteriorated patients in institutions, who are estimated at less than 4 per cent of all epileptic persons, but also the convulsive seizures that handicap a much larger number of afflicted persons in the community, and the still commoner, supposedly related psychic, vasomotor or irritative phenomena, such as migraine, visual disturbances and faint spells.

  2. The success of treatment by a diet high in fat and low in carbohydrate.

  3. The disagreement between reported fat values in the blood in epilepsy, some high and others low, as shown by the following tabulation:

Lennox and Cobb's exhaustive monograph on epilepsy indicates that reconciliation of the discrepant observations is difficult because of uncertainty, either on the part of the author or on that of the reader, as to the time at

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