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August 1932

LECITHIN AND CHOLESTEROL IN CEREBROSPINAL SYPHILIS INCLUDING DEMENTIA PARALYTICA AND TABES

Author Affiliations

NEW YORK

From the Department of Dermatology and Syphilology, New York Post-Graduate Medical School and Hospital and the Manhattan State Hospital.

Arch NeurPsych. 1932;28(2):399-404. doi:10.1001/archneurpsyc.1932.02240020151011
Abstract

Studies of the occurrence of lecithin and cholesterol in the blood and spinal fluid of patients suffering from the various forms of syphilis of the central nervous system show very different results. Active interest in these substances during the past decade has made us feel more and more the necessity for additional investigation. We have now completed analyses in seventy-eight cases (including tabes, cerebrospinal syphilis and dementia paralytica). Though this is too small a number for conclusive deductions, the results may be helpful.

The analytic methods employed were essentially those published in 1928 and 1929.1 All our patients were inmates of the Manhattan State Hospital. The blood and spinal fluid were drawn in the morning before breakfast. We studied four groups of patients:

  • Those suffering from cerebrospinal syphilis and dementia paralytica (untreated).

  • Those affected with tabes (untreated).

  • Those suffering from cerebrospinal syphilis, tabes and dementia paralytica at various stages

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