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November 1932

ENCEPHALITIS DISSEMINATA: A CLINICAL AND ANATOMIC REPORT OF A CASE WITH FEATURES AKIN TO MULTIPLE SCLEROSIS AND DIFFUSE SCLEROSIS

Arch NeurPsych. 1932;28(5):1072-1090. doi:10.1001/archneurpsyc.1932.02240050108007
Abstract

Since the great epidemics of von Economo's disease of the preceding two decades, instances of sporadic, nonepidemic encephalitis, unassociated with any known virus or linked with one (vaccinia, variola, measles, etc.), are being reported from all quarters in steadily increasing numbers. The present report is made not only with the purpose of adding a new and somewhat unusual example, but also because the material affords data we consider pertinent to the old and currently active controversy respecting the nature and true nosological significance of multiple sclerosis, as well as to similar questions in the realm of the more recently elaborated disease concepts relating to the leukencephalitides of a diffuse kind (diffuse sclerosis, Schilder's disease, progressive subcortical encephalopathy, etc.).

REPORT OF A CASE 

History.  —Mr. Z., aged 23, a buyer for a tobacco company, entered the Presbyterian Hospital on June 10, 1929, with the history that on the evening of May

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