Intracranial roentgen therapy rests on the differential action of roentgen rays on the various structures, normal and pathologic, inside the skull. Information about the effect of irradiation on the normal nervous system has been gathered from experiments with animals and from clinical observations during the treatment of pathologic conditions in man. This paper deals only with the former, reporting the results obtained from heavy dosage with roentgen rays on the brains of adult dogs. The exposures to the roentgen rays were given in the State Institute of Roentgenology, Radiology and Cancer Research in Leningrad, under the direction of Prof. M. I. Nemenov. Physiologic studies of cortical function before and after irradiation were carried out with the use of conditioned reflexes in the physiologic laboratory of Prof. I. P. Pavlov. Histologic examinations of the brains were made in the neuro-pathologic laboratory of Prof. W. Spielmeyer in Munich.
THE LITERATURE ON ROENTGEN
LYMAN RS, KUPALOV PS, SCHOLZ W. EFFECT OF ROENTGEN RAYS ON THE CENTRAL NERVOUS SYSTEM: RESULTS OF LARGE DOSES ON THE BRAINS OF ADULT DOGS. Arch NeurPsych. 1933;29(1):56–87. doi:10.1001/archneurpsyc.1933.02240070062004
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