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March 1933

Ether, cocaïne, hachich, peyotl et démence précoce: Essai d'exploration pharmacodynamique du psychisme des déments précoces.

Arch NeurPsych. 1933;29(3):680-681. doi:10.1001/archneurpsyc.1933.02240090250021

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In this monograph Deschamps relates his experiences with the use of ether, cocaine, hashish and peyotl for the purpose of "exteriorizing" the internal life of the patient with chronic dementia praecox. He conducted his researches on thirty-two cases of hebephrenic catatonia, carefully excluding the paranoid-delusional types; twenty-seven of the thirty-two patients were stuporous, negativistic and totally inaccessible to ordinary clinical approach. The author reviews the psychogenic theories of dementia praecox, contrasting them with the organic theory. He concerns himself especially with the theories that deal with the analogies between schizophrenic thinking and dreams, delirium and revery. He believes that the schizophrenic patient represents a mixture of true unchangeable organic deficit reaction with a psychogenic reaction based on "reversible lesions." It is the purpose of these pharmacodynamic procedures to break down the wall which the schizophrenic patient erects against the environment and so to determine by observation of his spontaneous activity

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