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The contents of this volume consist of four lectures: I. "Neurohypophyseal Mechanisms from a Clinical Standpoint"; II. "Posterior-Pituitary Hormone and Parasympathetic Apparatus"; III. "The Basophil Adenomas of the Pituitary Body and Their Clinical Manifestations (Pituitary Basophilism)"; IV. "Peptic Ulcer and the Interbrain." The fourth attempts to show that there is a neurogenic cause for acute perforative lesions affecting the esophagus, stomach and duodenum in the interbrain, where, in recent years, the cerebral centers for vegetative impulses have been placed. The evidence is not altogether convincing, but with the data at hand such an interpretation should be considered for what it is worth.