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April 1934

PSYCHOSES ASSOCIATED WITH PROBABLE INJURY TO THE HYPOTHALAMUS AND ADJACENT STRUCTURES: Effects of Solution of Pituitary and Pitressin Given Intraspinally

Author Affiliations

Towson, Md.

From the Sheppard and Enoch Pratt Hospital.

Arch NeurPsych. 1934;31(4):809-816. doi:10.1001/archneurpsyc.1934.02250040133009
Abstract

The occurrence of diabetes insipidus, obesity and hypersomnia in association with emotional and psychic disturbances has attracted the attention of neurosurgeons. Fulton and Bailey,1 in a thorough review of the literature, including a report of several cases of their own, pointed out that obesity and polyuria frequently occur in tumors involving the infundibulum. Hypersomnia, in some of their cases, seemed associated with tumor involving the floor of the third ventricle as well as the infundibulum. Cushing2 described a "hypersomnic" form of tumor involvement of the floor of the third ventricle by gliomatous lesions. Not infrequently in these cases there are encountered emotional and psychic disturbances of varying degree which may appear as outbursts of temper, persistent irritability, confusion, marked loss of memory, confabulation, bizarre behavior, habit deterioration, etc.

Two cases are reported in which the patients exhibited psychotic manifestations sufficient to cause them to be segregated in a

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