Little attention has been given to the central nervous system in reports of mushroom poisoning, and the literature contains few neuropathologic studies. The object of this paper is to review the neurologic manifestations and the neuropathologic observations hitherto reported and to present studies of the brain and the spinal cord in two cases.
REVIEW OF CLINICAL FINDINGS
Manifestations of involvement of the central nervous system have frequently been mentioned in reports of mushroom poisoning.Ford1 mentioned coma, cyanosis, a fall in temperature, convulsions and ocular symptoms. Six cases with one death were reported by Schürer.2 In the fatal case the eyes were fixed upward and to the left; there were clonic convulsions and then somnolence and coma, followed by death. Clark, Marshall and Rowntree3 noted vasomotor collapse, delirium, confusion, exaggerated reflexes, with a bilateral Babinski sign, rigidity and tremors and a temperature subnormal at first, later rising