Since the publication in 1882 of Raynaud's1 original description entitled "Observations on Local Asphyxia and Symmetrical Gangrene" there have been numerous factors reported as causal in this syndrome. Regardless of the etiology, Raynaud knew that the condition which he described was more prevalent in nervous women, a fact obtaining today and suggesting cortical or subcortical influence.
We propose to show that local asphyxia or abnormal vasoconstriction resulting in syndromes analogous to that of Raynaud may develop from stimuli arising at any level from the cerebral cortex down to the peripheral vessels themselves.
REPORT OF CASES
—F. W., a girl, aged 15, entered the University Hospital on Sept. 16, 1928, with the chief complaint of "difficulty in seeing." The mother stated that after the age of 12 this child had not developed physically as had her other child. The girl had never menstruated. The intellect had always been
PEET MM, KAHN EA. VASOMOTOR PHENOMENA ALLIED TO RAYNAUD'S SYNDROME. Arch NeurPsych. 1936;35(1):79–91. doi:10.1001/archneurpsyc.1936.02260010089006
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