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July 1936

OXYGEN SATURATION OF BLOOD DRAINING THE BRAIN AND THE LIMBS OF PATIENTS WITH EPILEPSY

Author Affiliations

BOSTON

From the Neurological Unit, Boston City Hospital, and the Department of Neurology, Harvard University Medical School. This paper is no. XVIII in a series entitled "Studies in Epilepsy." Aid in this research was received from the Harvard Epilepsy Commission.

Arch NeurPsych. 1936;36(1):13-18. doi:10.1001/archneurpsyc.1936.02260070021002
Abstract

We have been trying to determine what part, if any, cerebral anemia or anoxemia plays in relation to the seizures of epilepsy. Previous articles have dealt with the cerebral blood flow before and during epileptic seizures,1 with the effect on seizures of alteration of the oxygen tension of respired air,2 with the degree of anoxemia required to produce unconsciousness3 and with the oxygen saturation of arterial blood in epilepsy.4 The last-mentioned study indicated a mild degree of anoxemia in about half the patients examined. In the present paper we report observations of the oxygen saturation of venous blood drawn from an internal jugular vein, a basilic vein and a femoral vein.

Apparently, except for a preliminary report by one of us,5 an investigation of this nature has not been reported in medical literature.

MATERIALS AND METHODS  The patients examined were private patients or attendants at

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