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September 1936

Malarial Therapy of Neurosyphilis and Other Diseases of the Nervous System.

Arch NeurPsych. 1936;36(3):673. doi:10.1001/archneurpsyc.1936.02260090226019

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Abstract

This monograph embodies the author's experience with some 1,100 cases of various forms of syphilis of the central nervous system, treated by malaria in the Neurology Clinic of the Rostov University. Miniovich shows an extensive knowledge of the foreign literature and constantly compares his results and ideas with those expressed elsewhere, so that one gets a full exposition of the subject.

Both tertian and quartan malaria were used in the treatment. Among 220 cases of dementia paralytica complete remissions occurred in 21.8 per cent, incomplete remissions in 24.1 per cent and improvement in 22.3 per cent. There was no change in 28.1 per cent, and death occurred in 0.3 per cent. Miniovich explains that his unusually favorable results are due to the fact that in the patients treated the disease was fairly acute and recent.

Miniovich is in favor of a second course of malarial therapy but recommends a different

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