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This voluminous monograph, published as the sixth supplement of the Acta psychiatrica et neurologica, is based on investigations which Ask-Upmark carried out in the departments of anatomy, neurology and neurosurgery of the Harvard University Medical School. The anatomic studies, with a thorough review of the literature, are valuable. The comparative anatomic features of the carotid sinus were studied in sixty-one animals, representing twenty-seven species of mammals, birds, reptiles and amphibia. The important point is made that the carotid sinus is always observed at the internal carotid artery if the artery is present. In species in which no carotid artery is present the sinus is located at the base of the occipital artery, indicating that the carotid sinus may play an important rôle in regulating cerebral circulation. Interesting data are supplied regarding the variations in the bifurcation of the carotid artery and developmental malformations. The rete mirabile caroticum is described in
The Carotid Sinus and the Cerebral Circulation: An Anatomical, Experimental and Clinical Investigation, Including Some Observations on Rete Mirabile Caroticum. Arch NeurPsych. 1936;36(4):916. doi:10.1001/archneurpsyc.1936.02260100243013
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