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November 1936


Author Affiliations


From the Department of Nervous and Mental Diseases, the Northwestern University Medical School.

Arch NeurPsych. 1936;36(5):931-974. doi:10.1001/archneurpsyc.1936.02260110016005

VOLUME AND PRESSURE  One of the many observations dealing with physical laws governing cerebrospinal fluid pressure which need clarification is the meaning of the ratio between the removal of cerebrospinal fluid and the subsequent reduction in the cerebrospinal fluid pressure. It is needless for our purpose to quote extensively from the literature. It is sufficient to state that Ayala1 computed what he called a rachidial quotient by dividing the product of the amount of spinal fluid removed and the resulting pressure by the initial pressure. Later,2 he modified the quotient, dividing the difference between the initial and the final pressure by the quantity of cerebrospinal fluid removed. This is considered to be a numerical indication of the relative volume of the ventriculosubarachnoid spaces at the time of drainage, the volume of the blood and the elasticity of the meninges. Since Ayala considered the last factor to be relatively

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