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November 1936

Saggio di fisiologia del liquido cerebro-spinale (Critical Essay on the Physiology of the Cerebrospinal Fluid).

Arch NeurPsych. 1936;36(5):1153. doi:10.1001/archneurpsyc.1936.02260110238023

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In this monograph Disertori attempts to analyze critically the concepts regarding the method of formation of the cerebrospinal fluid. It is divided into ten chapters of one hundred and sixty-one pages, with a bibliography of fifteen pages. The site of formation, the circulation and the function of the fluid are dealt with in the last three chapters, and the usual ideas in regard to these subjects are expressed.

The first chapter discusses the two most commonly considered theories of the mode of formation of the fluid, namely, dialysis and secretion. Disertori states that the cerebrospinal fluid cannot be considered to be a dialysate of the serum unless the concentration of the various anions and cations in the two fluids satisfies the Donnan theory of membrane equilibrium. In the five succeeding chapters he discusses the distribution between the serum and the cerebrospinal fluid of chlorides, bromides, dextrose, other substances normally present

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