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March 1937

EFFECTS OF SODIUM AMYTAL AND OTHER DRUGS ON THE REACTIVITY OF THE HYPOTHALAMUS OF THE CAT

Arch NeurPsych. 1937;37(3):617-628. doi:10.1001/archneurpsyc.1937.02260150147008
Abstract

It is my purpose in this communication to report the effects of faradic stimulation of certain areas of the anterior portion of the hypothalamus and the motor cortex in cats and the modifications of these reactions under the influence of the systemic or the intrahypothalamic injection of sodium amytal or other drugs. Sixty-four cats were prepared in several series of experiments, according to the following technics:

METHODS 

Acute Experiments.— 

Series A 1.  —Hypothalamic Preparations: The cat was lightly anesthetized in an ether jar and the anesthesia continued by the use of an intratracheal cannula connected to a valved ether bottle. Both carotid arteries were isolated and encircled with separate loops of catgut for later approach. The Horsley-Clarke stereotaxic apparatus was then mounted, the skull trephined and an insulated nichrome electrode inserted into the hypothlamus, usually at the coordinate settings of anterior plane 14, right or left sagittal plane 2.5 and

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