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April 1937

Trigeminus Neuralgie: Een Anatomische en Klinische Studie (Trigeminal Neuralgia: An Anatomic and Clinical Study).

Arch NeurPsych. 1937;37(4):981-982. doi:10.1001/archneurpsyc.1937.02260160281030

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This monograph, emanating from Brouwer's clinic, is chiefly remarkable for a careful and well illustrated histologic study of the brain stem of a patient who died long enough after bilateral section of the trigeminal roots to permit degeneration to occur. To quote from the author's summary: "The motor nucleus was well formed on both sides; the number of cells was less as compared with that in normal persons. The cells of the main sensory nucleus were intact. The mesencephalic nucleus, both on the right and on the left, presented no changes. The mesencephalic tract on both sides showed a slight loss of thickness. The locus cœruleus was entirely intact on both sides. The mesencephalic tract must be autonomic. The locus cœruleus does not belong to the trigeminal system. The whole spinal tract was degenerated bilaterally."

In addition to this detailed study, there are a good history and an abstract of

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