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November 1937

SENSORY FUNCTIONS OF THE OPTIC THALAMUS OF THE MONKEY (MACACUS RHESUS): SYMPTOMATOLOGY AND FUNCTIONAL LOCALIZATION INVESTIGATED WITH THE METHOD OF LOCAL STRYCHNINIZATION

Author Affiliations

NEW HAVEN, CONN.; BUCHAREST, RUMANIA

From the Laboratory of Neurophysiology, Yale University School of Medicine.

Arch NeurPsych. 1937;38(5):913-926. doi:10.1001/archneurpsyc.1937.02260230011001
Abstract

Local strychninization of those structures of the central nervous system which subserve sensory functions results in marked, typical symptoms of sensory excitation. This has been established in previous experiments for the dorsal gray horns or pillars of the spinal cord and for the sensory cortex. In 1929 and 1930 we applied this method in a study of the sensory functions of the optic thalamus of the cat1 by injecting a minute quantity of a solution of strychnine into that part of the central nervous system. The present paper deals with a similar investigation of the optic thalamus of the monkey (Macacus rhesus). Here, again, it was found that local strychninization of various parts of the thalamus results in a typical syndrome and that a definite functional localization in this chief subcortical sensory center exists.

METHODS  The animals were all Macacus rhesus. Fifty-eight monkeys were used, each of which received

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