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January 1938


Author Affiliations


From the Department of Diseases of the Nervous System and the Department of Obstetrics, the Harvard University Medical School, the Boston Psychopathic Hospital, and the Massachusetts General Hospital.

Arch NeurPsych. 1938;39(1):24-36. doi:10.1001/archneurpsyc.1938.02270010034003

Our purpose in this study was to determine the rate of blood flow in patients with schizophrenia. The work of Blumgart1 has stimulated interest in studies on the velocity of blood flow. The circulation time, while it does not directly determine the velocity of blood flow, is the denominator in the equation distance of pathway/circulation time equals velocity of blood flow. It is assumed that, for practical purposes, the distance of a specific pathway is constant in different persons. Hence, the circulation time can be considered inversely proportional to the velocity of blood flow. In our work the sodium cyanide method of Robb and Weiss2 was used. The reasons that it is preferable to many other methods were given in their paper.2 Loevenhart, Lorenz, Martin and Malone,3 using the sodium cyanide method, reported a number of determinations of the circulation time (latent period, in their terminology)

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