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December 1938

CEREBRAL ANGIOMA ARTERIALEA Case in Which Migrainous Headache Was the Earliest Manifestation

Arch NeurPsych. 1938;40(6):1220-1232. doi:10.1001/archneurpsyc.1938.02270120170010

Tumors of the blood vessels of the central nervous system, although relatively uncommon, have aroused increasing interest among pathologists and clinicians in recent years. Inaccurate pathologic differentiation had caused much confusion with regard to them until Cushing and Bailey,1 in 1928, published a clinicopathologic study of the tumors of the blood vessels of the brain which helped to clarify the subject. They classified such tumors under two broad headings: (1) true neoplasms (hemangioblastomas), which occur most frequently in the cerebellum, and (2) angiomatous malformations, which may be chiefly capillary (telangiectasis), venous (angioma venosum) or arteriovenous (angioma arteriale) in composition.

The angiomatous malformations of clinical importance are the venous and arteriovenous angiomas. They are situated in the cerebral hemispheres and are primarily surface lesions. Cushing and Bailey estimated that they comprise about 1 per cent of all intracranial tumors. They show no predilection for any particular lobe, and their incidence