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April 1939

Zur Entdeckung der Insulinschocktherapie bei akuten Geisteskrankheiten, insbesondere bei der Schizophrenie.

Arch NeurPsych. 1939;41(4):869-870. doi:10.1001/archneurpsyc.1939.02270160225025

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Essentially, this booklet is a claim for priority. As early as 1923 the author treated a number of patients with conditions classified as dementia praecox, cryptogenic epilepsy and manic-depressive psychoses with large doses of insulin. In 1926 he gave a preliminary report before the medical society of Budapest and published his results in 1928 in the Archiv. für Psychiatrie und Nervenkrankheiten. The highest dose mentioned is 160 units. He produced hypoglycemia and coma. The occurrence of convulsions is not mentioned. Brief abstracts of 30 cases are given. It is not stated whether these cases represent a mere sample or the total number of patients treated. On the basis of these facts the author states that "insulin therapy is erroneously credited to Sakel: I should be given priority for insulin therapy of psychoses" (Fälschlich wird daher die Therapie mit Insulin Sakel zuerkannt, die Priorität der Insulintherapie der Psychosen gehört mir).