For a long time information concerning the intellectual functions of the human frontal lobes was necessarily derived from patients with spontaneous frontal lesions. The tumors, infections, injuries and atrophies which formed the groundwork for these studies carried with them the inherent complication of more or less widespread damage to the brain. Within recent years, Dandy has initiated the performance of lobectomies on human beings. He has thus made possible a new and useful method for the investigation of function of the human brain.
Only 1 patient has survived bilateral frontal lobectomy long enough to permit detailed study. The study of this patient has been reported on previously.1 The changes in the patient's behavior were massive. It is therefore of great interest to find that unilateral lobectomies produce virtually no alteration in human subjects. This fact receives emphasis from a similar striking difference between the results of unilateral and those
BRICKNER RM. CONSCIOUS INABILITY TO SYNTHESIZE THOUGHT IN A CASE OF RIGHT FRONTAL TUMOR AND LOBECTOMY: ANATOMIC CONSIDERATIONS CONCERNING THE NEURONS OF INTELLECT. Arch NeurPsych. 1939;41(6):1166–1179. doi:10.1001/archneurpsyc.1939.02270180094009
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