[Skip to Content]
[Skip to Content Landing]
June 1939


Author Affiliations


From the Section on Pathologic Anatomy (Dr. Baggenstoss) and the Section on Neurologic Surgery (Dr. Love), the Mayo Clinic.

Arch NeurPsych. 1939;41(6):1187-1206. doi:10.1001/archneurpsyc.1939.02270180115011

Tumors of the pineal body, because of their diversity in histologic structure and clinical manifestations and the difficulty of their operative removal, constitute an interesting and challenging group of neoplasms. Although the clinical picture of these tumors has been rather well established, the same cannot be said for their histogenesis. Haldeman,1 who reviewed the literature in 1927, found 113 cases that had been reported since 1800. The variety of names used to designate these neoplasms is astounding. In the cases that he collected the tumors were designated as fibromas, psammomas, psammosarcomas, sarcomas, gliomas, gliosarcomas, carcinomas, neuroepitheliogliomas, adenomas, adenocarcinomas, neurogliomas and pinealomas.

In the face of such confusion, the works of Marburg,2 Krabbe3 and Tilney and Warren4 and, more recently, the studies of del Rio Hortega,5 Berblinger,6 Horrax and Bailey7 and Globus and Silbert8 have done much to elucidate the histogenesis of the