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July 1939

The Treasury of Human Inheritance. Vol. IV: Nervous Diseases and Muscular Dystrophies. Pt. 1: Huntington's Chorea.

Arch NeurPsych. 1939;42(1):188. doi:10.1001/archneurpsyc.1939.02270190196020

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This volume is concerned primarily with the hereditary and genealogic aspects of Huntington's chorea, and the bulk of the material is a detailed summary of most of the case histories and pedigree charts contained in the literature up until 1932. The section dealing with incidence, age, sex, duration and associated disorders is derived apparently from the mass of cases reported in the literature, but there is no statement to indicate the specific sources of each statistical summary. Studies, particularly that of Vessie in 1932, have indicated that the disease was introduced into the United States from England, and Bell cites attempts to verify or disprove this assumption. One obtains the impression, however, that Huntington's chorea is exceedingly rare in England.

An interesting disclosure, to the reviewer at least, is the comparatively large number of cases of the disease in which the onset of symptoms occurred during the first two decades