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September 1939

Hérédité et Épilepsies.

Arch NeurPsych. 1939;42(3):593. doi:10.1001/archneurpsyc.1939.02270210231018

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From about four hundred books and articles Marchand has made uncritical selection of data which bear on the subject of heredity in epilepsy. Although he has no statistical data of his own, he accepts from widely differing reports the statement that whereas the incidence of epilepsy in the general population is about 2 per thousand, among the descendants of epileptic persons it is 37 per thousand and among the ascendants 65 per thousand. He also presents the evidence of Rosanoff and of Conrad showing the high proportion of cases in which both similar twins are affected. In spite of this seemingly convincing evidence for heredity, the author concludes that not epilepsy, but only the cerebral pathologic state which causes epilepsy, is inherited. This he calls "paraheredity." Thus, heredosyphilis is responsible in 4 or 5 per cent of cases of epilepsy and causes a cerebral fragility which can be transmitted for

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