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May 1940

TEMPORARY ARREST OF THE CIRCULATION TO THE CENTRAL NERVOUS SYSTEMII. PATHOLOGIC EFFECTS

Arch NeurPsych. 1940;43(5):961-986. doi:10.1001/archneurpsyc.1940.02280050105007
Abstract

In a preceding article,1 the symptomatic effects of temporary complete interruption of the blood flow to the central nervous system were reported. The following report deals with the pathologic changes occurring in the central nervous system of 12 cats subjected to varying periods of circulatory arrest and killed from two days to six weeks later. The material to be presented is thought to be of interest for two reasons. First, it deals almost exclusively with the late permanent neuropathologic changes, and not with the earlier evidences of injury, which may be reversible. Second, the experimental method employed permits an accurate correlation between the late pathologic changes and the time of the circulatory arrest. Reviews of the neurologic changes produced by anemia of the central nervous system have been published by de Buck and de Moor,2 Gomez and Pike,3 Cannon and Burkett,4 Gildea and Cobb5 and

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