With increasing knowledge of cerebral functions the difficulties of localization in cases of tumor of the brain tend to diminish. There remains, however, a large number of cases in which accurate localization and successful operation are hindered by the rapid evolution of the disease. In the majority of such cases cerebral swelling and cerebral edema play an important part; indeed, these two reactions of the brain tissue may be considered as one of the greatest obstacles to the diagnosis and treatment of tumors of the brain. It is perhaps largely on this account that, in spite of advances made in neurosurgery in recent years, the treatment of cerebral tumors is often not as favorable as it should be.
Histopathologic studies of the problems presented by cerebral tumors, among which the investigations of Cushing and Bailey, Hortega, Ostertag, Marburg, Globus and Roussy and Oberling may be mentioned, have added much to
SCHEINKER I. CEREBRAL SWELLING AND EDEMA ASSOCIATED WITH CEREBRAL TUMOR: A HISTOGENETIC AND HISTOPATHOLOGIC STUDY. Arch NeurPsych. 1941;45(1):117–129. doi:10.1001/archneurpsyc.1941.02280130127008
Customize your JAMA Network experience by selecting one or more topics from the list below.