Neither the clinical nor the pathologic features of Pick's disease are uniform. As von Braunmühl1 stated, "each case [of Pick's disease] suggests new problems." The clinical and pathologic pictures in the case here recorded are unique and are therefore of unusual interest.
REPORT OF CASE
History (Dr. Levitin).
—G. O., aged 57, a white woman of Irish extraction, was admitted to the Psychiatric Institute of the University of Illinois on July 7, 1938. The history revealed that the patient's father died at the age of 76, about four years after he began to slip mentally. He became melancholy in the last nine months of his life and was childish and difficult to look after. One sister had epilepsy between the ages of 17 and 47. There were 11 siblings, of whom the patient was the eighth.The patient was always a popular, attractive woman with "a lovely disposition." She