The question whether the entity described by Kinnier Wilson should be expanded to include additional symptoms and signs reported by others in similar cases has been debated in the scientific literature for the past two decades. The case presented here is of interest because of the nature of the onset, the absence of tremor, the clinical methods used in an attempt to establish the presence of hepatic damage and the mental status and personality changes of the patient.
REVIEW OF LITERATURE
A brief review of the development of the concept of hepatolenticular disease reveals that the condition aroused interest before the time of Wilson and is probably not so rare as is generally believed.Strümpell1 in 1878 described a case in which the disease seemed to resemble multiple sclerosis but which was a typical instance of this condition; in 1883 Westphal2 reported 2 similar cases of a disorder
BABCOCK CG, BROSIN HW. HEPATOLENTICULAR DEGENERATION: REPORT OF A CASE. Arch NeurPsych. 1941;46(3):431–439. doi:10.1001/archneurpsyc.1941.02280210057004
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