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March 1942

SPINA BIFIDA WITH MENINGOCELE: Occurrence in Two Children of the Same Family

Author Affiliations


From the Department of Pediatrics, Long Island Division, Kings County Hospital.

Arch NeurPsych. 1942;47(3):474-476. doi:10.1001/archneurpsyc.1942.02290030132012

We are reporting the occurrence of spina bifida cystica with meningocele in 2 successive siblings of the same family. Such familial repetition is unusual. According to Bucy,1 the cystic form of spina bifida occurs about once in every thousand births. The cases forming the basis of his report occurred singly in families. Woltman2 found that in 2 of 187 cases there was definite or presumptive evidence of spina bifida in other members of the same family. In 3 of Cutler's3 series of 62 cases of spina bifida with cephalocele there was a postive history of spina bifida or hydrocephalus in other siblings. Sachs,4 in his discussion of congenital anomalies of the nervous system, referred to a family in which 3 successive children had spina bifida. Murphy,5 in his excellent survey, reported 4 cases of recurrent familial spina bifida. Earlier reports of the presence of spina

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