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March 1943


Author Affiliations


From the Division of Nervous and Mental Diseases, University of Minnesota.

Arch NeurPsych. 1943;49(3):398-413. doi:10.1001/archneurpsyc.1943.02290150086004

Whenever a new disease of the nervous system is identified, one of the most commonly used criteria of its seriousness is the fatality rate in a large series of cases. This is by no means the best measure of the resulting damage, since even in cases of recovery there may occur physical and mental residuals which in themselves may be as disastrous as the fatalities. However, in order adequately to evaluate such sequelae, it becomes necessary to follow a large number of cases over a period of years. Such a study has, as yet, not been attempted for equine encephalomyelitis, since the actual recognition of this disease in man has been relatively recent. Even its absolute identification in horses did not occur until 1931, when Meyer and his co-workers1 isolated a virus as the etiologic agent. Since the recognition of the equine virus and the discovery that neutralizing antibodies

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