Progressive peroneal muscular atrophy associated with bilateral atrophy of the optic nerve is of rare occurrence. Only 6 observers appear to have reported cases of this type. Twenty-six years after his original description of peroneal muscular atrophy Tooth1 stated that he never had seen this symptom complex. Vizioli,2 in 1879, described a family in which the father, aged 59, and his 2 sons, aged 26 and 6 years, presented atrophy of the muscles of the calves; the hands were affected later in 2 of the patients. Both the father and the older son had progressive impairment of vision and finally became totally blind. Ophthalmoscopic examination showed bilateral optic nerve atrophy. The younger brother apparently retained normal vision, but he was examined only during the early stages of the disease.
Similar cases were reported by Sainton,3 Gordon,4 Ballet and Rose,5 Taylor6 and Krauss.7 Sainton
MILHORAT AT. STUDIES IN DISEASES OF MUSCLE: XIV. PROGRESSIVE MUSCULAR ATROPHY OF PERONEAL TYPE ASSOCIATED WITH ATROPHY OF THE OPTIC NERVES; REPORT ON A FAMILY. Arch NeurPsych. 1943;50(3):279–287. doi:10.1001/archneurpsyc.1943.02290210057003
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