Elsewhere one of us (L. D.)1 has presented evidence to show that a psychosis due to estrogen deficiency exists and responds promptly to appropriate therapy. To prove the existence of a psychosis due to androgen deficiency is more difficult because of the vagueness of the diagnostic criteria. The evidence for the existence of such a psychosis will be reviewed in the present paper, and the results of therapy in new cases will be described.
For some years, numerous psychiatrists and endocrinologists have been interested in the treatment of involutional melancholia in the male with androgens. Because of the comparative rarity of the disorder and the difficulty of the diagnosis, it is not reasonable to expect a single hospital to contain a large number of patients suitable for study. It is only when the results of many investigations are pooled that figures for statistical treatment can be collected.
DANZIGER L, SCHROEDER HT, UNGER AA. ANDROGEN THERAPY FOR INVOLUTIONAL MELANCHOLIA. Arch NeurPsych. 1944;51(5):457–461. doi:10.1001/archneurpsyc.1944.02290290044007
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